Secure Online Purchase
Buy Birth Control
Making birth control more affordable
and accessible!
U.S. Name: Activelle
Active Ingredients: Estradiol Hemihydrate and Norethisterone Acetate
Brand Manufacturer: Novo Nordisk
Manufacturer Location: Denmark
Estradiol & Norethisterone is used in the treatment of menopause and other hormone related issues.
Local NameStrengthManufacturerSizePriceQtyTotal Price
Activelle1mg / 0.5mgNovo NordiskBrand1x28$35.00$0.00
The FDA allows the importation of up to three months supply for personal use.
A valid prescription is required to buy Activelle online.
Activelle® is an oral birth control that comes in tablet form and is often used to treat menopause symptoms. Activelle® is a combination pill. This means that it contains both Estrogen and Progestin. Estrogen in the form of Estradiol Hemihydrate is used in combination with Norethisterone Acetate, a type of Progestin.
Activelle is sold under various brand names like Activella, Clinorette and Estalis.
Conditions Treated by Activelle
Activelle® is mainly used as a hormonal treatment to treat menopause, vaginal dryness and to prevent Osteoporosis. It can also be used as birth control.

The tablets are used after menopause to reduce the side effects of menopause. This includes reducing moderate to severe hot flushes, calming changes in and around the vagina and preventing your chances of getting Osteoporosis. Talk to your healthcare provider to make sure Activelle® is suitable for your symptoms. You may find that treating changes to the vagina might be more effective with a topical vaginal product rather than oral tablets. This might be the case if the only reason you are using Activelle® is to treat changes in or around the vagina and there are no other symptoms to treat.

The same goes for preventing and treating Osteoporosis using Activelle®. Many women are susceptible to weak bones (Osteoporosis) after menopause. Your health care adviser will be able to advise you on different treatment options. It could be that a medicine without Estrogens might be better for you if you are using Activelle® only as a treatment for Osteoporosis and have no other symptoms.
What you should know before taking Activelle®
Like all medications Activelle® is not suitable for people with specific conditions. If you do take Activelle® then you will have to be monitored when taking Activelle® more closely.

If you have high blood pressure, angina, heart disease, high cholesterol, kidney disease, asthma, epilepsy, migraine, depression, diabetes, gallbladder disease or uterine fibroids then tell your doctors about them before you start taking Activelle®. The same goes for if you have had a hysterectomy (uterus removed). Activelle® contains Estradiol and Progestin compounds so it might not be suitable for you or you may need to use an adjusted dosage.

You should not take Activelle® is you are pregnant or planning to get pregnant.
Activelle® birth control is in the FDA pregnancy category X. This means that Activelle® can cause birth defects in an unborn baby. The Estradiol and Progestin compounds in Acivelle® can also affect milk supply so you should not take it when breast feeding either.

Always consult with your doctor before taking this birth control or menopause treatment.
Activelle® warnings
Activelle® should be avoided in some cases. Read the pack insert for a full list of warnings. Prescription medication and over the counter meds (including vitamins) can interact with Activelle® so it’s important to let your doctor know about all the other medications and supplements that you take.

When taking Activelle® you should do regular self-breast examinations. Using hormone medications for menopause or birth control can increase your chances of developing breast lumps and breast cancer.

Activelle® does not protect against sexually transmitted diseases.
Activelle® Dosage Information
  • Typical dosage recommendations
    Take Activelle® (Estraiol Hemihydrate and Norethisterone Acetate) exactly as directed by your doctor. Normally you take 1 tablet a day with water, ideally at the same time of day. Activelle® comes in a convenient disc dispenser so it’s easy to keep track of where you are in the month. If you do not understand the directions, ask your pharmacist, nurse, or doctor to explain them to you.

    The Activelle® disc dispenser should be stored at room temperature away from moisture, heat, and direct light.
  • Missing a dose
    Don’t panic if you miss a dose. If you are only a few hours late then take the missed dose as soon as you remember. Continue with your course of treatment like normal and take the next dose of Activelle® as planned. If it is almost time for the next dose then it’s better to skip the missed dose. Otherwise you can overdose. Simply take the next dose like planned.
  • Overdosing
    In the case of missed doses please consult with your doctor. Unlike some birth control and menopause hormone therapies it is advised NOT to double dose on this medication if you miss a dose. Symptoms of Activelle® (Estraiol Hemihydrate and Norethisterone Acetate) overdose may include nausea, vomiting, and withdrawal bleeding may occur in females. If you overdose by mistake and experience some of these symptoms then contact an emergency room or poison control center for advice on what to do.
Activelle® Side Effects
Taking Activelle® as birth control or for menopause treatment can cause side effects. Some side effects of Activelle® are serious and require medical assistance and other side effects of Activelle® are minor and can be ignored as long as they don’t cause you too much discomfort.

Minor Activelle® side effects can include nausea, vomiting, tenderness/ enlargement of the breasts, general weakness and swelling of the hands or feet. Just because you experience one of these side effects does not mean that you will experience all of them. Activelle® can also cause skin discoloration like spotty darkening of the skin, particularly on the face. It can also make eyes dry so you may experience difficulty in wearing contact lenses. Taking Activelle® can also affect your menstruation. It can cause vaginal discomfort, changes in menstrual cycle, painful menstruation or break-through bleeding.

Activelle® contains Estradiol which is a form of Estrogen hormone that can increase the risk of developing endometrial hyperplasia. This is where the lining of the uterus thickens. In most people this condition is harmless but in some people it can lead to cancer of the lining of the uterus. Activelle® also contains Norethisterone, a type of Progestin, which when combined with Estradiol lowers the risk of developing this condition.

All the above conditions are uncomfortable but are normally not serious. You should let your doctor know about all the side effects of Activelle especially any unusual vaginal bleeding. If they don’t bother you too much then you can continue treatment as long as your doctor confirms this with you.

Here is a list of serious Activelle® side effects that need urgent medical advice.
Sometimes you can have an allergic reaction to Activelle®. It is rare but if you experience difficulty breathing, closing of the throat, swelling of the face/tongue/lips or hives then go to the emergency room or contact an emergency doctor. Allergic reactions to medications are very serious.

Other serious side effects to Activelle® include shortness of breath, chest pains, swollen or painful leg or legs (sometimes the leg or legs can appear red) and vomiting. Abnormal vaginal bleeding, pain or swelling of the abdomen, severe headache, dizziness or faintness, changes in vision or speech and yellowing of the skin or eyes also require urgent medical attention.
Activelle® Drug Interactions
The use of Activelle® should be monitored closely if you are taking anticoagulant blood thinners. Warfarin (Coumadin) is an example of blood thinner medication. You may require a dosage adjustment or special monitoring during treatment or your doctor might suggest avoiding Activelle® altogether.

It’s also a good idea to talk to a pharmacist before starting anything new, even vitamins, minerals, and herbal products to make sure they will not interact with what you are already taking.

The information about Activelle® on this site is purely educational; it does not replace a doctor’s consultation.
Affordable & quality birth control
At you can buy birth control online at better prices. Our mission is to give you affordable birth control and menopause meds so you can take care of your menstrual health and know that you're getting the best deal. Our online birth control and menopause medications are dispensed by reputable pharmacists and shipped all over the world.
We're happy to answer your questions. Take advantage of our excellent and personal customer service.
Ask the Pharmacist
Receive personal and immediate responses to your questions from our resident pharmacist.
Proper Brand Medication
Trademarks and registered marks are the properties of their respective companies. Copyright © 2015 I-L-S Ltd. All Rights Reserved.
We accept Visa, Mastercard & American Express
  • Twitter
  • Pinterest
  • Facebook is a secure online pharmacy selling birth control, morning after & menopause meds
Frequently asked questions, ordering and shipping information
Compare birth control methods and birth control prices
Read about women's issues and birth control news
Our best selling birth control brands include Yaz, Yasmin, Mirena, Diane, Activelle
Compare prices on birth control products with this price compariosn chart.